abstract：:The molecular defects in the catalase gene, levels of m-RNA and properties of the residual catalase studied by scientists are reviewed in human (Japanese, Swiss and Hungarian) and non-human (mouse and beagle dog) acatalasemia with reference to the bioinformatics. Japanese acatalasemia-I, the G to A transition at the f...

journal_title：Acta medica Okayama

authors： Ogata M,Wang DH,Ogino K

更新日期：2008-12-01 00:00:00

abstract：:In the present study, we examined the dynamic of school-health-based parasite control and the related socio-economic influences. This is an ecological study based on data from 46 prefectures in Japan. The exponential decay of Ascaris lumbricoides prevalence was calculated by iterative least-squares method. Pearson's c...

journal_title：Acta medica Okayama

authors： Kurosawa CM,Ito T,Takaki J,Wang BL,Wang DH,Takigawa T,Ogino K

更新日期：2008-10-01 00:00:00

abstract：:The purpose of this study is to compare the performance of laparoscopic partial nephrectomy (LPN) with and without clamping of the renal artery and to evaluate the impact of clamping on postoperative renal function. A total of 20 patients underwent LPN, 13 without and 7 with clamping of the renal artery. The 2 groups ...

journal_title：Acta medica Okayama

authors： Kobayashi Y,Saika T,Manabe D,Nasu Y,Kumon H

更新日期：2008-08-01 00:00:00

abstract：:Oxidative stress, including the reactive oxygen or nitrogen species generated in the enzymatical oxidationor auto-oxidation of an excess amount of dopamine, is thought to play an important role in dopaminergic neurotoxicity. Dopamine and its metabolites containing 2 hydroxyl residues exert cytotoxicityin dopaminergic ...

journal_title：Acta medica Okayama

authors： Miyazaki I,Asanuma M

更新日期：2008-06-01 00:00:00

abstract：:A rare complication of percutaneous endoscopic gastrostomy (PEG) is gastrocolocutaneous fistula which usually occurs after replacement of the PEG tube. As tube feeding is directly delivered to the transverse colon, patients typically present with a sudden onset of transient diarrhea within minutes after PEG tube feedi...

journal_title：Acta medica Okayama

authors： Okutani D,Kotani K,Makihara S

更新日期：2008-04-01 00:00:00

abstract：:We defined the maximum-tolerated dose (MTD) of chemoradiotherapy (cisplatin (CDDP) with 5-fluorouracil (5-FU) and concurrent chemoradiotherapy) for Chinese patients with esophageal cancer. Twenty-one previously untreated patients with primary esophageal cancer were entered into this study. Escalating doses of CDDP wit...

journal_title：Acta medica Okayama

authors： Lin Q,Gao XS,Qiao XY,Zhou ZG,Zhang P,Chen K,Zhao YN,Asaumi J

更新日期：2008-02-01 00:00:00

abstract：:We conducted a randomized controlled trial involving Japanese junior college students aimed at investigating the effects of a single session of alcohol health education concerning the effects of alcohol, alcohol-related health problems, and drinking behavior. Students were randomly assigned to an intervention (n=38) o...

journal_title：Acta medica Okayama

authors： Geshi M,Hirokawa K,Taniguchi T,Fujii Y,Kawakami N

更新日期：2007-12-01 00:00:00

abstract：:The innate immune system provides immediate defense against infection and serves as the first line of host defense during infection. In innate immunity, leukocytes such as neutrophils and macrophages recognize and respond to pathogens in a non-specific manner. Therefore, the recruitment and activation of leukocytes ar...

journal_title：Acta medica Okayama

authors： Matsukawa A

更新日期：2007-10-01 00:00:00

abstract：:We conducted a survey for glucose-6-phosphate dehydrogenase (G6PD) deficiency using blood samples from male outpatients of a local hospital in southern Vietnam. Most of the samples were from the Kinh (88.9%), the largest ethnic group in Vietnam, with a small number (11.1%) coming from the K'Ho, Chauma, Nung, and Tay m...

journal_title：Acta medica Okayama

authors： Matsuoka H,Thuan DT,van Thien H,Kanbe T,Jalloh A,Hirai M,Arai M,Dung NT,Kawamoto F

更新日期：2007-08-01 00:00:00

abstract：:Neuronal apoptosis is involved in neurodegenerative diseases such as Alzheimer's disease and Parkinson.s disease. An efficient means of preventing it remains to be found. Some n-3 polyunsaturated fatty acids (PUFAs) such as docosahexaenoic acid (DHA, 22 : 6n-3) and eicosapentaenoic acid (EPA, 20 : 5n-3) have been repo...

journal_title：Acta medica Okayama

authors： Wu Y,Tada M,Takahata K,Tomizawa K,Matsui H

更新日期：2007-06-01 00:00:00

abstract：:We compared muscle strength between Japanese men with and without metabolic syndrome. We used data for 323 Japanese men with metabolic syndrome and 893 Japanese men without the syndrome. Metabolic syndrome was defined by a new criterion in Japan, and the parameters for muscle strength, i.e. grip strength, leg strength...

journal_title：Acta medica Okayama

authors： Miyatake N,Wada J,Saito T,Nishikawa H,Matsumoto S,Miyachi M,Makino H,Numata T

更新日期：2007-04-01 00:00:00

abstract：:We report herein a case with acute hepatitis due to hepatitis B virus genotype Ae, concurrent with amebic colitis. A 39-year-old homosexual Japanese man was admitted to our hospital with jaundice. Laboratory tests showed an elevation of transaminase and positivity for hepatitis B surface antigen and IgM-type antibody ...

journal_title：Acta medica Okayama

authors： Miyake Y,Iwasaki Y,Ishikawa S,Tatsukawa M,Nawa T,Kato J,Takaki A,Kobashi H,Sakaguchi K,Shiratori Y

更新日期：2007-02-01 00:00:00

abstract：:Clostridium perfringens infection is a very rare cause of massive intravascular hemolysis, but it should always be kept in mind, since only early treatment can rescue patients from an otherwise rapidly fatal outcome. We report a case of a 78-year-old diabetic male who was admitted complaining of general fatigue, dark ...

journal_title：Acta medica Okayama

authors： Ohtani S,Watanabe N,Kawata M,Harada K,Himei M,Murakami K

更新日期：2006-12-01 00:00:00

abstract：:The term ectopic varices is used to describe dilated portosystemic collateral veins in unusual locations other than the gastroesophageal region. We recently experienced a rare case of ectopic varices that developed in the right diaphragm and ruptured into the pleural cavity. A 68-year-old female with hepatocellular ca...

journal_title：Acta medica Okayama

authors： Matsui M,Kojima A,Kakizaki S,Nagasaka K,Sohara N,Sato K,Takagi H,Mori M,Ohno Y

更新日期：2006-08-01 00:00:00

abstract：:We report herein the disappearance of macular hard exudates after the introduction of hemodialysis in diabetic patients. A 62-year-old woman and a 52-year-old man with diabetes mellitus showed hard exudates in the macula of the left eyes. Both patients had previously undergone panretinal photocoagulation in both eyes....

journal_title：Acta medica Okayama

authors： Matsuo T

更新日期：2006-06-01 00:00:00

abstract：:Deficiency of glucose-6-phosphate dehydrogenase (G6PD) causes acute hemolytic anemia triggered by oxidative drugs such as primaquine. It is therefore essential in malaria-endemic areas for malaria patients to be confirmed for their G6PD activity before taking primaquine. The WST-8 method, a newly established screening...

journal_title：Acta medica Okayama

authors： Arai M,Kosuge K,Kawamoto F,Matsuoka H

更新日期：2006-04-01 00:00:00

abstract：:We attempted to prepare colloidal iron within tissues by means of microwave irradiation. Mouse tissue blocks were fixed with a mixture of paraformaldehyde and ferric chloride in a cacodylate buffer, immersed in a cacodylate buffered ferric chloride solution, and irradiated in a microwave processor. Colloidal iron was ...

journal_title：Acta medica Okayama

authors： Nakatani S,Naito I,Momota R,Hinenoya N,Horiuchi K,Nishida K,Ohtsuka A

更新日期：2006-02-01 00:00:00

abstract：:This study focused on the effects of different intervals between sessions of a hypercholesterolemia education class on post-intervention outcomes. The same comprehensive group-programme contents on hypercholesterolemia were delivered either monthly (for 6 months) or twice-monthly (for 3 months) by the same teaching pr...

journal_title：Acta medica Okayama

authors： Kotani K,Saiga K,Sakane N,Kurozawa Y

更新日期：2005-12-01 00:00:00

abstract：:We examined whether ambulatory ability before surgery might influence the post-operative D-dimer level after total hip arthroplasty (THA). One hundred two patients with hip osteoarthritis receiving THA were included in the current study. The patients were all female, and their ages ranged from 45 to 81 (average 65.0 +...

journal_title：Acta medica Okayama

authors： Sasaki K,Senda M,Ishikura T,Ota H,Mori T,Tsukiyama H,Hamada M,Shiota N

更新日期：2005-10-01 00:00:00

abstract：:We describe a novel method for immunofluorescent detection of multiple antigens in a single paraffin-embedded tissue section. We hypothesized that if fluorescent dyes are resistant to heat treatment, then thermal inactivation of immunoglobulins during antigen detection procedures might make it possible to use multicol...

journal_title：Acta medica Okayama

authors： Suzuki T,Tate G,Ikeda K,Mitsuya T

更新日期：2005-08-01 00:00:00

abstract：:The potential relationships between biofilm formation and pathogenicity of Enterococcus faecalis in urinary tract infections (UTI) were investigated. Over a 12-year period from 1991 through 2002, a total of 352 E.faecalis isolates were collected from patients with complicated UTI (one isolate per patient) at the urolo...

journal_title：Acta medica Okayama

authors： Seno Y,Kariyama R,Mitsuhata R,Monden K,Kumon H

更新日期：2005-06-01 00:00:00

abstract：:A 68-year-old Japanese man with a history of linitis plastica carcinoma of the stomach and subsequent gastrectomy 8 years previously presented with lower abdominal pain. Radiological and endoscopic examinations showed multiple submucosal nodular lesions similar to Crohn's disease in the ileocecal area. A firm diagnosi...

journal_title：Acta medica Okayama

authors： Tanakaya K,Takeuchi H,Yasui Y,Takeda A,Umeda Y,Murakami I

更新日期：2004-08-01 00:00:00

abstract：:To elucidate the mechanism by which hyperbaric oxygen (HBO2) induces electrical discharge, changes in the extracellular concentrations of GABA and glutamate were measured every 5 min using a microdialysis technique in rats during a period of exposure to HBO2 (5 atm abs). Electrical discharge was observed at 28 +/- 4 m...

journal_title：Acta medica Okayama

authors： Zhang S,Takeda Y,Hagioka S,Goto K,Morita K

更新日期：2004-04-01 00:00:00

abstract：:Pressure distribution patterns of the seating interface on the multi-cell air cushion (ROHO High Profile) of 36 adults with spinal cord injury (SCI) (Neurological level Th3 -L1) were measured at different air pressure levels by a pressure mat measurement system. Stress distribution relative to the inflated air pressur...

journal_title：Acta medica Okayama

authors： Hamanami K,Tokuhiro A,Inoue H

更新日期：2004-02-01 00:00:00

abstract：:This retrospective study evaluated the safety and efficacy of using polidocanol with X-ray fluoroscopy for percutaneous sclerotherapy of venous malformations of the limbs, head, and neck. The subjects were 16 of 18 patients who presented to our department with venous malformations. Two patients were excluded because t...

journal_title：Acta medica Okayama

authors： Mimura H,Kanazawa S,Yasui K,Fujiwara H,Hyodo T,Mukai T,Dendo S,Iguchi T,Hiraki T,Koshima I,Hiraki Y

更新日期：2003-10-01 00:00:00

abstract：:Despite the current diagnostic and serologic testing for SLE, the interval between the onset of symptoms and the diagnosis is still long. In this study, we aimed to show the interval between the initial symptoms and the diagnosis of SLE and to investigate the presence of any relationship between the interval and the i...

journal_title：Acta medica Okayama

authors： Ozbek S,Sert M,Paydas S,Soy M

更新日期：2003-08-01 00:00:00

abstract：:Radiation damage to normal brain tissue induced by interstitial irradiation with iridium-192 seeds was sequentially evaluated by computed tomography (CT), magnetic resonance imaging (MRI), and histological examination. This study was carried out in 14 mature Japanese monkeys. The experimental area received more than 2...

journal_title：Acta medica Okayama

authors： Mishima N,Tamiya T,Matsumoto K,Furuta T,Ohmoto T

更新日期：2003-06-01 00:00:00

abstract：:Several specific assays have been developed for the measurement of etoposide in biological fluids. As large samples are required for high sensitivity, these systems are not appropriate for a pediatric practice. In the present study, however, an improved method for the determination of serum levels of the anticancer dr...

journal_title：Acta medica Okayama

authors： Kato Y,Mawatari H,Nishimura S,Sakura N,Ueda K

更新日期：2003-02-01 00:00:00

abstract：:Transforming growth factor-beta1 (TGF-beta1) exerts potent immunosuppressive effects. In this study, we investigated the potential role of TGF-beta1 produced by hepatocellular carcinoma (HCC) cell lines in immunosuppression mechanisms. Using the Mv1Lu cell-growth inhibition assay and an enzyme-linked immunosorbent ass...

journal_title：Acta medica Okayama

authors： Mouri H,Sakaguchi K,Sawayama T,Senoh T,Ohta T,Nishimura M,Fujiwara A,Terao M,Shiratori Y,Tsuji T

更新日期：2002-12-01 00:00:00

abstract：:A pilot study was conducted to assess the efficacy and feasibility of daily low-dose cisplatin with concurrent thoracic irradiation for clinically unresectable non-small-cell lung cancer (NSCLC). Patients with inoperable NSCLC who had poor risk factors such as advanced age, poor performance status, poor lung function,...

journal_title：Acta medica Okayama

authors： Takata I,Ueoka H,Kiura K,Tabata M,Takigawa N,Katayama H,Takemoto M,Hiraki Y,Harada M,Tanimoto M

更新日期：2002-10-01 00:00:00

abstract：:Two kinds of surgical models of small intestinal transplantation (SITx) in rats, namely heterotopic (HIT) and orthotopic transplantion (OIT), have been reviewed. In OIT, the small intestine of the recipient is removed and the transplanted intestine replaces it in continuity. On the other hand, in the HIT model, the sm...

journal_title：Acta medica Okayama

authors： Nakao A,Tahara K,Inoue S,Tanaka N,Kobayashi E

更新日期：2002-04-01 00:00:00

abstract：:The effects of immobilization stress on the pharmacokinetics of omeprazole were studied in rats. The immobilization stress for 30 or 60 min immediately after oral administration of the drug caused an increase in the time to reach the maximum concentration. However, such stress did not alter the area under the plasma c...

journal_title：Acta medica Okayama

authors： Watanabe K,Matsuka N,Okazaki M,Hashimoto Y,Araki H,Gomita Y

更新日期：2002-02-01 00:00:00

abstract：:It is recognized that sustained ischemia-induced hyperactivity is related to abnormalities in dopamine function. However, it is unclear that dopaminergic neurotransmission triggers such ischemia-induced hyperactivity. Therefore, the relationship between dopaminergic neurotransmission and ischemia-induced hyperactivity...

journal_title：Acta medica Okayama

authors： Yamamoto T,Araki H,Futagami K,Kawasaki H,Gomita Y

更新日期：2001-10-01 00:00:00

abstract：:We developed a method for human identification of forensic biological materials by PCR-based detection of a human-specific sequence in exon 3 of the myoglobin gene. This human-specific DNA sequence was deduced from differences in the amino acid sequences of myoglobins between humans and other animal species. The new m...

journal_title：Acta medica Okayama

authors： Ono T,Miyaishi S,Yamamoto Y,Yoshitome K,Ishikawa T,Ishizu H

更新日期：2001-06-01 00:00:00

abstract：:With the development of new treatments, there is an increasing need for early diagnosis of sporadic Alzheimer's disease. Therefore, biological markers allowing positive diagnosis early in the course of the disease are highly desirable. Cerebrospinal fluid levels of protein tau were shown to be significantly increased ...

journal_title：Acta medica Okayama

authors： Engelborghs S,De Deyn PP

更新日期：2001-04-01 00:00:00

abstract：:A sharp rise in the number of patients with infectious gastroenteritis was observed in the 25th week of year 1996 in the Takahashi-Ashin district by researchers with the Infectious Disease Surveillance Program for tuberculosis and other infectious diseases in the Okayama Prefecture. This sharp rise occurred coincident...

journal_title：Acta medica Okayama

authors： Tsumagari K,Yamamoto H,Suganuma N,Kato M,Ikeda S,Imai K,Kira S,Taketa K

更新日期：2000-12-01 00:00:00

abstract：:Fracture of the penis is an unusual blunt traumatic injury of the erect penis. Twenty-five such cases, treated at the 2 main urological departments in the town of Varna between 1984 and 1999, were analyzed retrospectively. The average annual incidence in this series was 0.33 per 100,000 inhabitants. Most of the injuri...

journal_title：Acta medica Okayama

authors： Hinev A

更新日期：2000-10-01 00:00:00

abstract：:The Thoratec (Vectra) polyurethane vascular access graft (TPVA) is among the most recent additions to the list of materials used to construct prosthetic grafts for vascular access during hemodialysis. We give the TPVA very high marks, and recognize the utility of such a graft for use in hemodialysis. However, the stro...

journal_title：Acta medica Okayama

authors： Nakao A,Miyazaki M,Oka Y,Matsuda H,Oishi M,Kokumai Y,Kunitomo K,Isozaki H,Tanaka N

更新日期：2000-04-01 00:00:00

abstract：:This research aims to establish the effect of working conditions on the appearance of varicose veins. The epidemiological study was carried out on 1,324 examinees, 530 males and 794 females, employed in 5 highly represented groups of professional activities in Rijeka (catering, trade, light industry, heavy industry an...

journal_title：Acta medica Okayama

authors： Kontosić I,Vukelić M,Drescik I,Mesaros-Kanjski E,Materljan E,Jonjić A

更新日期：2000-02-01 00:00:00

abstract：:In recent years it has been reported that free oxygen radicals play an important role in the pathogenesis of degenerative diseases and that antioxidant vitamins such as vitamins E or C prevent their harmful effects. In this study, we evaluated the following: Erythrocyte susceptibility to lipid peroxidation; the role o...

journal_title：Acta medica Okayama

authors： Dinçer Y,Akçay T,Konukoglu D,Hatemi H

更新日期：1999-12-01 00:00:00